Peptides for Weight Management
Peptides studied in metabolic contexts — including FDA-approved GLP-1/GIP receptor agonists and investigational compounds involved in appetite regulation and fat metabolism.
Educational content only. The information on this page is for educational purposes only and does not constitute medical advice, diagnosis, or treatment recommendations. Always consult a qualified healthcare professional before making decisions about any medication or health intervention. Regulations and product availability vary by country and jurisdiction. Learn about peptide safety & regulation →
Tirzepatide
Tirzepatide is an FDA-approved dual GIP/GLP-1 receptor agonist (Mounjaro, Zepbound) studied for type 2 diabetes and chronic weight management, with extensive Phase 3 trial data.
Semaglutide
Semaglutide is an FDA-approved GLP-1 receptor agonist (Ozempic, Wegovy) with robust clinical evidence for type 2 diabetes management and chronic weight loss.
Retatrutide
LY3437943
Retatrutide is an investigational triple GLP-1/GIP/glucagon receptor agonist in Phase 3 TRIUMPH trials, demonstrating significant weight reduction in Phase 2 research.
Mazdutide
IBI362
Mazdutide is a dual GLP-1/glucagon receptor agonist approved in China for weight management and T2D; currently in Phase 2 US trials. Not FDA-approved.
Survodutide
BI 456906
Survodutide (BI 456906) is an investigational dual GLP-1/glucagon receptor agonist in Phase 3 trials for obesity and MASH; not yet approved by any regulatory authority.
Cagrilintide
CagriSema (combination)
Cagrilintide is a long-acting amylin analog studied in combination with semaglutide (CagriSema) in Phase 3 REDEFINE trials. It is not yet approved by any regulatory authority.
Tesamorelin
Egrifta / Egrifta WR
Tesamorelin (Egrifta) is an FDA-approved GHRH analog indicated for HIV-associated lipodystrophy. It stimulates endogenous GH release and has Phase 3 trial data supporting its approved use.
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